Reformulation and Scientific Evaluation of CUSOCO: A Traditional Toothpaste Formula from Classical Tamil Literature towards treatment of Halitosis

In order to achieve the multi-claim products required for dental-health-care and hygiene, it is indispensable formulator use a wide range of ingredients however, with advent technology chemically synthesised are not demand in market as they have side effects considered unsafe human use. This places quite number demands on PBNPs development process. Use innovations areas pharmaceutical contributed significantly formulation superior efficacy well other attributes that may contribute clinical response patient acceptability. Improved tolerability, along conditioning signals, should encourage compliance oral hygiene. Cuminum cyminum seeds being habitually used traditional cuisines different cultures. India, both whole ground form ingredient make dishes without perceptive medicinal knowledge/ properties behind. Kerala, decoction cumin drinking (Jeera water). Tamilnadu, key Rasam. Fruit Solanum lycopersicum one important savoury vegetable Indian cuisines. The oil Cocos nucifera fruits cooking Kerala TamilNadu. present study, composition (paste) prepared by mixing 2 drops S. fruit juice, C. 1g seed powder were tested 100 subjects felt bad breath. Results study was found be effective controlling breath (odour) 74 after treatment (period trial) except 09 83 who diabetic.
 Keywords: Oral hygiene; breath; halitosis; cyminum; lycopersicum; nucifera; CUSOCO;